After leaving university, Lee was in charge of operations at his family business specialising in the manufacture of precision glass and silica components, as well as the design and assembly of silica process machinery. The company also operated a specialist manufacturing service for assemblies used in analytical instruments. Later, Lee became Operations Manager for a microfluidics start-up, and later joined The Dolomite Centre Limited after it had won a £2m award under the DTI’s Micro & Nano Technology Manufacturing Initiative initially as the Head of Operations. In 2020 he took over the role of the Managing Director of Dolomite Microfluidics.
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