Company Overview:
Branca Bunús Ltd is an Irish UCD spin-out company developing and commercialising high-performance non-viral gene delivery technologies to accelerate the development and manufacturing of cell and gene therapies. Our flagship technology is a patented HPAE (Hyperbranched Poly(β-amino ester)) transfection platform, engineered to deliver superior transfection efficiency, high lentivirus titres, and excellent scalability compared to conventional reagents (e.g., PEI and lipid-based systems). The platform results in a GMP-ready and cost-effective product, BrPERfect® for virus, which is ideal for large-scale lentivirus vector production.

Key Product & Application Focus:
> BrPERfect® Transfection Reagent – high-efficiency non-viral vector
> Primary application: Lentivirus production in HEK293/293T cells
> Compatible with suspension and adherent cell systems
> Suitable for serum-free and large-scale bioreactor manufacturing
> Enables efficient, cost-effective upstream production for ex vivo CAR-T workflows
> Strategic focus: Lentivirus market — currently the strongest validated performance of our technology.

Our Strengths:
> Proven performance in Asia: validated by multiple biotech and academic partners
> High viral titres: demonstrated superior yields compared to conventional reagents
> Cost-effective: lower dosage and more affordable than leading commercial reagents
> GMP-ready product: scalable for clinical and commercial manufacturing
> Excellent stability & simplified process: BrPERfect® forms a stable complex for at least 3 hours at room temperature, providing flexibility in production scheduling; easy to operate with robust performance in large-scale manufacturing.

Branca Bunus Ltd

Org chart

Teams

Offices