The California Institute for Biomedical Research (Calibr) is a first-of-its-kind, nonprofit translational research institute dedicated to accelerating the next generation of medicines. Affiliated with Scripps Research—among the most innovative institutes worldwide—we spearhead drug discovery from a steady flow of pioneering science. Our self-sustaining model encourages broad and bold exploration with far-reaching goals, yet rapid transition of our most successful, high-impact programs into the clinic. We pursue audacious and imaginative ideas—bridging scientific and technological advances to develop new medicines for unmet medical needs. 

Our pipeline programs range from cancer to infectious diseases and from discovery to early clinical trial stages, all aimed at preventing disease and healing humans around the world. 

We bring together leaders in research, drug development, and business to answer important biological questions and develop new interventions to treat, cure, and prevent disease. Our infrastructure and expertise extend from high-throughput screening and protein engineering to pharmacology and clinical development. 

Calibr’s research space includes a newly renovated 35,000 square foot facility in La Jolla, CA, which houses over 100 interdisciplinary scientists and staff with state-of-the-art instrumentation. This infrastructure, combined with Calibr’s drug discovery expertise, enables projects rooted in novel therapeutic mechanisms to progress from the laboratory through preclinical development and ultimately to the clinic through commercial, federal, or foundation partnerships.

Life Sciences

Calibr at Scripps Research

Calibr at Scripps Research's headquarters in San Diego, CA, United States

This department focuses on advancing research and development in biological discovery and related scientific fields.

Discovery Sciences

The Research and Development team at Calibr at Scripps Research plays a pivotal role in the drug discovery process, bridging scientific exploration with clinical application. This interdisciplinary team, comprising experts in medicinal chemistry, clinical operations, and compound management, focuses on identifying and optimizing new therapeutic compounds aimed at treating various diseases. By leveraging state-of-the-art facilities and cutting-edge technologies, the team drives projects from initial discovery through to early-stage clinical trials, ensuring that innovative solutions are developed to meet pressing medical needs.

Research and Development

This department focuses on conducting research and analysis to support various projects and initiatives.

Research Department

This department conducts advanced scientific research to drive innovation and discoveries.

Scientific Research

The Leadership Team at Calibr plays a crucial role in guiding the vision and strategic direction of the organization, ensuring that innovative research translates into impactful medicines. Composed of experts in pharmaceutical development, clinical operations, and corporate strategy, the team collaborates to oversee research initiatives, drive drug discovery projects, and establish partnerships. By fostering a culture of bold exploration and scientific rigor, they aim to accelerate the development of therapies for unmet medical needs across diverse disease areas.

Leadership Team

This department conducts advanced research and development through the collaboration of postdoctoral researchers and associates.

Research Development

This department manages and oversees the planning and execution of clinical trials and studies.

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Other teams

Research and Development

Research Department

Scientific Research

Leadership Team

Research Development

Clinical Operations