Lawrence Chasin

Dr. Lawrence Chasin is a Professor of Biological Sciences at Columbia University. Professor Chasin’s research is aimed at discovering the sequence signals in DNA that control the expression of Human genes. His earliest major contribution was to help found the field of mammalian cell genetics where he demonstrated that genetic manipulation could succeed in mammalian cells just as it had in microorganisms. Professor Chasin’s seminal works led to new fields of study: “gene amplification” and “nonsense-mediated decay.” Prof. Chasin has consistently pushed the development and use of new technologies. This includes the creation of Chinese Hamster Ovary host cell lines produced by Prof. Chasin’s laboratory that are now the gold standard for the commercial production of therapeutic monoclonal antibodies and are used by nearly all biopharmaceutical companies worldwide for research on, and/or the production of, a majority of licensed human protein therapeutic products.