Uttum joined Coopers & Lybrand, Botswana in 1973 and became a partner in 1982. He was later appointed as the first Senior Partner of PricewaterhouseCoopers in Botswana after concluding a successful merger between Coopers & Lybrand and PricewaterhouseCoopers. In 2008, Uttum retired from PwC and later took office as Director General of the National Strategy Office of Botswana reporting directly to the Presidency from 2010 and served until 2019. Uttum has served as President of the Botswana Institute of Chartered Accountants, a former board member of the Bank of Botswana and former board member of Botswana Insurance Holdings. He has also served as the first Chairman of the Botswana Export Development and Investment Authority and as a founding member of the University of Botswana Foundation. He was honoured by Rotary International with the Paul Harris Fellowship and a special Rotary Centennial Service Award for Professional Excellence. He received these accolades as recognition for his professional achievement, his demonstration of high ethical standards, community and vocational service and dedication to service above self.