Thomas Walpole is a highly experienced scientist specializing in protein expression and structural biology. Currently serving as Lead Scientist at Constructive Bio since February 2025, Thomas previously held the position of Associate Principal Scientist at Bicycle Therapeutics, where significant advancements were made in a higher-throughput mammalian expression system and the resourcing of protein reagents for drug discovery. Prior experience includes roles as Senior Scientist at Charles River Laboratories, focusing on purification and crystallization methods for novel reverse transcriptase enzymes, and as a Research and Development Scientist at both Biomodal (formerly Cambridge Epigenetix) and Cambivac Limited, contributing to critical projects in enzyme production and vaccine development, respectively. Thomas's academic credentials include a PhD in Mitochondrial Biology from the University of Cambridge and a BSc (Hons) in Biochemistry from Liverpool John Moores University.
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