Cynata Therapeutics Limited (ASX: CYP) is an Australian clinical-stage stem cell and regenerative medicine company focused on the development of therapies based on Cymerus™, a proprietary therapeutic stem cell platform technology. Cymerus™ overcomes the challenges of other production methods by using induced pluripotent stem cells (iPSCs) and a precursor cell known as mesenchymoangioblast (MCA) to achieve economic manufacture of cell therapy products, including mesenchymal stem cells (MSCs), at commercial scale without the limitation of multiple donors. 
Cynata’s lead product candidate CYP-001 met all clinical endpoints and demonstrated positive safety and efficacy data for the treatment of steroid-resistant acute graft-versus-host disease (GvHD) in a Phase 1 trial.  Clinical trials of Cymerus MSC products in osteoarthritis (Phase 3) and in severe complications arising from COVID-19 (Phase 2) are currently ongoing. Planning is also underway for further clinical trials of Cymerus MSC products in GvHD (through licensee Fujifilm), critical limb ischemia, idiopathic pulmonary fibrosis, renal transplantation, and diabetic foot ulcers. In addition, Cynata has demonstrated utility of its Cymerus MSC technology in preclinical models of numerous diseases, including the clinical targets mentioned above, as well as asthma, heart attack, sepsis, acute respiratory distress syndrome (ARDS) and cytokine release syndrome.

Life Sciences

Therapeutics

Cynata Therapeutics

Cynata Therapeutics' headquarters in Cremorne, Australia

Dr Kilian Kelly

This department oversees data protection strategies and manages the development of manufacturing processes.

Data Protection and Process Development

This department oversees compliance with regulations and scientific standards related to products and services.

Regulatory Affairs

This department provides strategic direction and oversees the overall management of the organization.

Executive Leadership

This department oversees clinical processes and business strategies to enhance operational efficiency and effectiveness.

Cynata Therapeutics

Org chart

Teams

Data Protection and Process Development

Regulatory Affairs

Executive Leadership

Clinical and Business Operations

Offices

Cynata Therapeutics

Org chart

Teams

Data Protection and Process Development

Regulatory Affairs

Executive Leadership

Clinical and Business Operations

Offices

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