Emergex, a clinical-stage, privately-held biotechnology company headquartered in Abingdon, UK, with an operating subsidiary in Doylestown, Pennsylvania, USA, is pioneering the development of 100% synthetic T cell-priming immune set-point vaccine candidates that harness and direct the body’s natural CD8+ T cell immune response to destroy and clear pathogen-infected cells in order to provide protection against some of the world’s most urgent health threats. First indications pursued are against infectious diseases caused by: [i] viruses, amongst which are Betacoronavirus, Dengue Fever and Universal Influenza A, including pandemic influenza, as well as [ii] intra-cellular bacteria.

Emergex has a growing proprietary pipeline of innovative T cell-priming set-point candidates that have the potential to deliver rapid, broad (strain and variant agnostic) and long-lasting prevention and therapy to reduce serious illness associated with infectious disease. Emergex has completed two Phase I clinical trials for products against: [i] Dengue (which may also be disease-modifying for other members of the Flaviviridae virus family) and [ii] Betacoronavirus disease. Other programmes in development include candidates for Universal (including pandemic) Influenza, Zika, Chikungunya, Smallpox/Monkeypox, Hand/Foot/Mouth Disease a booster for Yellow Fever, and Francisella tularensis (intra-cellular bacterium).  

Emergex’s T cell-priming immune set-point candidates combine two proprietary technologies, [i] an empirically determined library of pathogen-derived protein fragments expressed on the surface of pathogen-infected cells (forming the MHC Class I expression “ligandome” library) using Immunotope Inc’s immunoproteomics technologies, and [ii] a self-assembling, ultrasmall carbohydrate-passivated nanocluster carrier system designed to deliver synthetic peptides to the skin-resident immune system via micro-needles to elicit a robust T cell response. 

Biotechnology

Emergex Vaccines

Emergex Vaccines' headquarters in ABINGDON, United Kingdom

Thomas Rademacher

László Fekete

Natalie Sands Fcca

Brian Pfister

This department ensures the quality and reliability of products through testing and analysis.

Emergex Vaccines

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Emergex Vaccines

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