The Alain Cribier Institute is the first global center dedicated exclusively to heart valve diseases.

Based in Rouen, France, the Institute carries forward the revolutionary legacy of Professor Alain Cribier—inventor of the TAVI, a breakthrough that has already saved over 3 million lives worldwide. We are a unique powerhouse for research, clinical care, high-level training, and innovation.

Valvular heart disease is a major global health challenge, affecting 30 million people today—a figure set to double by 2050. To meet this urgency, our mission is to transform French scientific excellence into a universal standard of care that is safer, more effective, and less invasive.

Our 4 Strategic Pillars:

RESEARCH: Accelerating innovation, from molecular biology to AI, to better predict and treat valvular pathologies.

CARE: Designing integrated patient pathways for early diagnosis and equitable access to cutting-edge treatments.

TRAINING: Passing on excellence to the next generation of global experts through the Medical Training Center (MTC).

DISSEMINATION: Raising awareness among the public and policymakers (Annual "Souffle au Cœur" Day).

Joining the Alain Cribier Institute means supporting audacious science for a profound human impact. Together, let’s repair hearts without breaking them.

Institut Alain Cribier

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Institut Alain Cribier

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