Sheilah O'Brien

Managing Principal at Knowesis

Sheilah founded Knowesis in late 2007. She exercises executive oversight for all aspects of the company including business development, service delivery, and day-to-day operations in keeping with the company’s “sell and deliver” philosophy. Her 25-year career in health analytics and data management has spanned direct clinical research (therapeutics and devices), clinical informatics, business decision support, performance measurement and enterprise reporting. Her client base has spanned multiple entities within the Department of Defense, the Department of Veterans Affairs (VA), and the Military Health System (MHS). She provided leadership to commercial engagements, specifically in the commercial pharmaceutical and biotech sectors (Pfizer, AstraZeneca, Sanofi).

As a U.S. Air Force veteran, Ms. O’Brien is the recipient of the Star Warfighter award.

The Star Warfighter Award is awarded to government contractors that support the safety and well-being of individuals serving in the armed forces post-war and during deployment. Ms. O’Brien holds a Master of Public Administration and is a Six Sigma Yellow Belt.

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