Sells and develops robots for cell biology and small organism applications:

1) Automated zebrafish egg injections
Using a special grid, zebrafish eggs are aligned such that microinjection can take place at an unprecedented speed of ~1 egg per second. 
Latest publication: https://doi.org/10.2144/btn-2023-0062
2) Zebrafish 2-4 pdf embryo injections, same efficiency, twice the speed, and reduced learning curve as compared to manual injections. Manuscript in preparation.
3) Egg / organism Sorting, for zebrafish, medaka, frog eggs, Hyalella Azteca etc.
One paper: https://tinyurl.com/yc8me2we 
4) Small organism imaging, for 3-5 dpf zebrafish, medaka or other organisms. 2 minutes per image stack, fully autonomous. Manuscript in preparation.
Brightfield, fluorescent, confocal and lightsheet.
5) Automated 3D tissue culture
Mixing polymers with a cell suspension allows for instant cell tissue creation at predefined locations in a hydrogel.
The use of these injected cell spheroids in high-throughput quantitative cancer invasion screens is described in Biomaterials, 2012. http://dx.doi.org/10.1016/j.biomaterials.2011.09.049

Development of new methods, just ask :)

Life Science Methods

Jan de Sonneville

This department focuses on innovative research and development initiatives to advance organizational goals.

Life Science Methods

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Life Science Methods

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Teams

Research and Development

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