Founded in 2007, Lotus Separations, LLC is a privately owned partner in small‑molecule purification. Our mission is people‑first: help scientists get the highest‑purity material quickly, reliably, and cost‑effectively—so their projects keep moving.

We specialize in preparative and analytical chromatography across SFC and HPLC, chiral and achiral, from milligrams to kilograms. Much of our work uses supercritical fluid chromatography (SFC), a greener approach that leverages liquid CO2 to reduce organic solvents while improving speed and efficiency.

We’re cGMP‑capable for preclinical, clinical, and IND‑enabling phases, with what we believe is a first‑of‑its‑kind dedicated GMP SFC purification lab. That capability is paired with rigorous QA, documented traceability, clear communication, and on‑time delivery.

How we work
 - Collaborative by design: open, solution‑oriented exchanges to tailor methods to your goals.
 - Ingenuity under pressure: we develop and optimize methods to crack tough separation challenges.
 - Deadline‑driven: we work evenings and weekends when needed to meet critical timelines.
 - Value‑focused: high purity without high overhead—efficient methods, fair pricing, transparent scopes.


What we deliver
 - Rapid turnaround of high‑purity APIs, intermediates, and reference materials.
 - Chiral resolutions and complex impurity/isomer separations.
 - Method development and scale‑up from discovery to IND support.
 - Comprehensive documentation (batch records, CoAs) aligned with cGMP expectations.

Who we serve
 - Biotech, pharma, CRO/CMO partners, and academic teams who need responsive expertise and dependable results.

Our commitment
 - Quality you can trust, speed you can plan around, and a team that treats your milestones like our own.

Let’s talk about your next purification challenge—and how we can help you solve it, fast.

Lotus Separations, LLC

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Lotus Separations, LLC

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