Omer Klein started their work experience in 2004 at the Israel Ministry of Defense, where they managed the office of a unit responsible for overseeing the activities of the Israeli Security Forces. Omer stayed there until 2007. In 2009, they co-founded and became the CEO of FotoBar, a gallery website. Omer left FotoBar in 2012. From 2013 to 2016, Omer served as the Head of Product at Glance - Pic Your Group, a photo sharing mobile app for private groups. Since 2017, Omer has been the Chief Executive Officer at medflyt, a technology platform that connects home health agencies with healthcare professionals, simplifying the staffing process.
Omer Klein attended Reichman University from 2009 to 2012, where they pursued a Bachelor of Laws (LL.B.) degree with a focus on Finance, General.