Sally Khambule began her mining career in 2005 as a Management Trainee at Driefontein Gold. In 2006, she was awarded a bursary by AngloGold Ashanti to study B-tech. She was appointed as a Metallurgical Engineer two years later, and then she moved into mining projects in 2010, where she was responsible for the implementation of RIP projects. In 2013, she joined DRD Gold as a Plant Superintendent of the new flotation plant.
The core areas accredited to her experience include managing processing plants, commissioning, running pilot plants and projects and field services.