Novai
Jonathan Young is a seasoned data scientist with extensive experience in machine learning and image processing, currently employed at Novai since May 2021, where responsibilities include developing machine learning and image processing pipelines for retinal image alignment and segmentation. Prior experience includes roles at Massive Analytic, PRA Health Sciences, IXICO, and the Institute of Psychiatry, Psychology & Neuroscience, focusing on data science development, clinical trial site risk prediction, and liaising with researchers for data access. Jonathan has a strong academic background, holding a PhD and MRes in Medical Image Computing from UCL, alongside an MSc in Computing and a BSc in Physics from the University of Birmingham.
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Novai
Novai is a British biotechnology start-up, commercialising DARC Technology, an exploratory retinal biomarker for use in Age-related Macular Degeneration (AMD) & glaucoma clinical studies. DARC combines an innovative patented biologic with a state-of-the-art AI algorithm and uses standard imaging equipment to identify cellular level diseaseactivity. DARC Technology can be used to measure the impact of current and future therapeutics and interventions by assessment of disease activity whilst identifying non-responders to existing and new interventions, resulting in the avoidance of costly, ineffective or un-required medical management. DARC helps to stratify patients in clinical trials, resulting in the creation of enriched patient cohorts, consisting of those at highest risk of rapid disease progression.DARC has been developed by Professor M Francesca Cordeiro at University College London through Wellcome Trust funding and is now approved as an exploratory biomarker by the FDA & MHRA. Following further analysis of Phase II data, several other indications may follow, including Multiple Sclerosis, Alzheimer’s Disease, Parkinson’s Disease, Diabetes Mellitus and Cancer.