Robert Benjamin Stein

Robert Stein is a medical scientist with over 40 years of pharmaceutical and biotech R&D leadership experience. He played a pivotal role in the discovery and development of Sustiva®, Fablyn®, Viviant®, PanRetin®, TargRetin®, Promacta® and Eliquis® and lead the discovery of over a dozen immuno-oncology-directed monoclonal antibodies, vaccines, and cell therapies progressing through clinical development. He consults broadly regarding drug discovery and development and serves on a number of Boards of Directors, both public and private. Since 2018, he has been is an Operating Partner at Samsara Biocapital and serves as acting head of R&D for MimeDx, acting CSO for MiroBio, and Scientific Advisor to Autobahn Labs, Inc. and to the Drug Development Institute at Ohio State University. Dr. Stein served as CSO and President of R&D for Agenus, Inc., a immuno-oncology company based in Lexington, MA from 2014 – 2018, and lead efforts which have advanced over a dozen clinical stage monoclonal antibodies, two of which are nearing BLA filing. He is a founder of AgenTus, a cell therapy spin-out from Agenus. Prior to joining Agenus he held a number of progressively responsible senior management positions including CSO & SVP of Research for Ligand Pharmaceuticals, EVP of Research & Preclinical Development for Dupont Merck, President and CSO for Incyte Pharmaceuticals, President of Roche Palo Alto and CEO of KineMed. From 1981 to 1990, Dr. Stein began his pharmaceutical career at Merck, Sharp and Dohme. He holds an M.D. and a Ph.D. in Physiology & Pharmacology from Duke University and is board-certified in anatomic and clinical pathology.