Pragma Bio (previously known as VastBiome) exists to find cures for undruggable immunological disorders. They use real-world data and synthetic biology to map out multi-omic signatures associated with clinical outcomes in order to produce microbial-derived small molecules with therapeutic potential.

Biotechnology

Pragma Bio

The South San Francisco office focuses on cutting-edge biotech research and development in immunology and bioinformatics.

South San Francisco

Pragma Bio's headquarters in San Carlos, CA, United States

Kareem Barghouti

Kovi Bessoff

Peter McCaffrey

Ayin Vala

Mohamed Donia

Grazia Piizzi

Ken Blount

Milad Alucozai

Wasim Malik

Elaine Stracker

Mohan Iyer

Nadim Ajami

Phil Jones

The Advisory Team at Pragma Bio provides expert guidance and strategic insights to support the company’s mission of discovering cures for undruggable immunological disorders. Leveraging their extensive experience, these advisors assist in shaping research directions, optimizing clinical strategies, and identifying opportunities for innovation in microbial-derived therapeutics.

Advisory Team

The Research and Science Team at Pragma Bio focuses on discovering and developing natural product-based therapies for immunological disorders. They utilize real-world data and synthetic biology to analyze multi-omic signatures and identify microbial-derived small molecules with therapeutic potential. Team members collaborate across disciplines, integrating expertise in product discovery, chemistry, bioinformatics, and immunology to drive innovative research and translate findings into clinical applications.

Research and Science Team

The Leadership Team at Pragma Bio is responsible for setting the strategic direction of the company and overseeing its operations in the quest to target undruggable immunological disorders. Comprised of co-founders with expertise in AI, technology, biology, and operations, the team drives innovation, ensures effective collaboration across departments, and fosters a culture of scientific excellence to translate real-world data into groundbreaking therapies.

Pragma Bio

Org chart

Board & advisors

Teams

Advisory Team

Research and Science Team

Leadership Team

Offices

Pragma Bio

Org chart

Board & advisors

Teams

Advisory Team

Research and Science Team

Leadership Team

Offices

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