Laure Coulomb has a diverse work experience in the field of bioprocessing and enzymology. They started their career as an R&D researcher in Enzymology at IOI-Loders Croklaan Oils B.V. in 2011. During this time, they optimized immobilized lipases and tested their performance in batch mode and packed bed reactors.
In 2013, Coulomb joined Novozymes as an Enzymology and synthetic chemistry trainee, where they focused on glycosyl hydrolases and contributed to a patent application. They purified enzymes using ion exchange and copper chelated resins.
They then moved to MedImmune in 2013, where they specialized in downstream processes for biopharmaceutical manufacturing. They focused on process scale-up purification and technology transfer, running campaigns from clarification to formulation for fermentation broths of 50 to 200 liters.
In 2016, Coulomb joined Johnson Matthey as a Biocatalysis researcher, working on a project to develop a general working flow process using immobilized transaminases to produce chiral amines. They implemented tools for enzyme immobilization and scaled up fermentation for commercial enzyme production. They later became a Research scientist in bioprocessing, developing and scaling up recipes and processes for upstream and downstream enzyme production.
Currently, Coulomb is working at Protera Biosciences as the Head of DSP engineer. They lead bioprocess development for DSP operations, collaborating with teams to optimize fermentation and DSP processes. They also prepare technical reports, data summaries, and regulatory documentation.
Laure Coulomb attended the Institut national des Sciences appliquées de Toulouse from 2008 to 2013, where they earned a degree in Génie Chimique et Alimentaire with a field of study in Ingénierie biochimique. Prior to that, they attended classe préparatoire aux grandes écoles Lycee Bellevue from 2006 to 2008, where they completed a Licence degree with a field of study in Physique, Chimie et science de l'ingenieur.
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