Salsa Biotherapeutics offers site-specific cargo attachment via a stable covalent bond using a simple chemical (small molecule) reagent. The inherent covalent bond stability of the Salsa Bio linker provides a route to avoid off-target toxicity. Excitingly, the approach avoids current issues related to ADC manufacturing complexity, potentially offering better scalability and lower cost of goods. 

The technology also presents a straight-forward platform to create dual-cargo ADCs, combining payloads with orthogonal methods of action in order to circumvent patient drug resistance.

Salsa Biotherapeutics

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