Saltgrass Capital is a $150M early-stage venture capital firm investing in transformative AI technology across the healthcare industry. We back B2B SaaS companies focused on clinical innovation and workforce optimization - powering the future of care delivery, operational efficiency, and data intelligence.

We are not medical device investors. Our sweet spot is software: AI-native platforms, intelligent automation, data infrastructure, and interoperability solutions that improve outcomes and system performance at scale.

Led by experienced operators and technologists, Saltgrass brings deep healthcare, AI, and go-to-market expertise. We invest at the Pre-Seed, Seed and Series A stages, with initial checks between $1M–$5M, and support our founders with strategic guidance, technical depth, and access to a wide healthcare ecosystem.

If you're building bold, responsible, enterprise-grade healthcare AI - we’d love to meet you.

AI/ML

Enterprise Software

Health Care

Venture Capital

Saltgrass Capital

Brian Litten

This department oversees the strategic direction and overall management of the organization.

Saltgrass Capital

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Saltgrass Capital

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