ScriptBio AI is building a causal AI-driven gene discovery platform for aging-related diseases, starting with knee osteoarthritis, a condition affecting 365M+ people worldwide with no disease-modifying therapy.

Our platform integrates foundation models fine-tuned on single-cell transcriptomics with a multi-layer causal inference pipeline to separate true disease drivers from aging correlates. The result: prioritized therapeutic gene targets with computational evidence of causality, not just correlation.

Our delivery strategy pairs AI-discovered targets with CRISPR-engineered iPSC-derived mesenchymal stem cells that act as living drug factories, deployed directly to the joint.

ScriptBio AI

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ScriptBio AI

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