SDA BIO is known as a supplier of vaccine adjuvants, 3 O/W, 3 W/O/W/, 4 W/O, 7 Nano/Microemulsions from 20 to 80 nm, 7 Polymer Microgels, self-emulsifying/assembling delivery/adjuvants for biologics, oil-in-water, ~150nm, ~100nm, ~40nm (IMS, microemulsion, or emulsion based immunosol), water-in-oil-in-water, ~300nm, water-in-oil, <1000nm, latex nanoparticle, 80-100nm, lipid nanoparticle, polymer gel nanoparticle (oil-in-polymer). We have multiple partnerships in commercializing soluble immunostimulants and systemic or complex adjuvants. 

Oil-in-water vaccine adjuvant can be supplied as oil phase for stir combination with aqueous antigen as self-emulsification; or it can be provided as emulsified form for customers to do further dilution with their antigen. The transparent nanoemulsion adjuvant can also be provided as oil phase SDA7749, or pre-emulsified forms for further diluting with antigen at ratios of 1:2, 1:3 or 1:5, known as IMS 4580, IMS 6050, and IMS 13X, IMS 25X.  We also distribute various TLR agonists and Polysaccharides as Immunostimulants.  

Our squalene based O/W 100~150 nm (AS110) and 40 nm (AS40) human vaccine adjuvants are self-emulsifying oil phase, free of microfluidizer or high gear homogenizer.  Our lipid nanoparticle delivery system (LNP) and cationic o/w nano-emulsion (CNE) are self-assembling. CAS40 is transparent formulation with particle size ~40 nm;  CAS110 is emulsion type of 100 nm in size.  Our squalene based nanoemulsion is extremely stable, for as long time as > 1 year under as high temperature as 42 degree C. 

Both emulsion and polymer gel based adjuvants can serve as diluent of live attenuated vaccines.

SDA BIO provides alum-emulsion dual adjuvant on demand, as well as saponin emulsion.  Final containers are radiation sterilized.

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