TopoGEN is a research diagnostics company that provides innovative products and services for researchers working with topoisomerases and engaged in mechanism based drug discovery and development.   The company was created by topo research active scientists who understand the needs and the restraints placed on other cancer researchers or those working in areas peripheral to topoisomerases.  Top-selling products include:

-Drug Screening Kits to identify topoisomerase active drugs for use in cancer chemotherapy and antibacterial applications 
-Assay Kits for assaying prokaryotic and eukaryotic topoisomerases (type I, II, IV, gyrase), both in vitro and in vivo
-A complete line of DNA substrates and DNA cleavage targets, topoisomerase inhibitors, topoisomerase antibodies, and kit replenishment reagents

Our contract screening service offers you powerful, mechanism based custom screens developed and conducted entirely in house. Our cell based (in vivo) screens for detecting topoisomerase I and II poisons in the context of the cancer cell represents the new gold standard for identification of novel anti cancer agents.

Since the early 1990s TopoGEN has maintained a dedicated clientele around the world. We offer substantial product support, data interpretation and consultation advice.  When you become our customer, we become your partner in research. We review your data and offer valuable input. Please contact us for further information about how we can assist your research goals.

TopoGEN, Inc.

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