The VIB Switch Laboratory is part of VIB Center for Neuroscience Leuven, KU Leuven and VIB.AI. Our research focuses on understanding the mechanisms gearing protein folding and misfolding and their relation to human disease. In particular, we are investigating how protein aggregation affects the interactome by suppressing native interactions but also by introducing novel aggregation-specific interactions. These latter are especially relevant as they are usually associated with gain of function activities such as neurotoxicity (neurodegeneration).



VIB Switch Laboratory

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VIB Switch Laboratory

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