THE PROBLEM. 
The inability to consistently and affordably produce high-quality advanced therapies limits their global reach. At the bench, generating enough mammalian cells remains the primary constraint, from 3D cell assays to translational research and early-stage bioproduction. The root cause is consistent: poor oxygen delivery and harsh microenvironments in conventional culture systems prevent cells from reaching natural tissue-level densities and quality.

OUR SOLUTION. 
XDemics is developing the High-Density Cell Respiration (HDCR™) platform to overcome the oxygen delivery and shear stress limitations of conventional cell culture systems, enabling direct control of pericellular oxygen at any setpoint and achieving up to 100-fold higher cell densities with improved function and quality. Our Expansify™ respiring cultureware and Profusion™ bioreactor products (under development) utilize HDCR™ to support workflows from early discovery to commercial production.  By eliminating oxygen transfer limitations and shear stress as core constraints, XDemics enables predictable, linear scaleup from 96-well plates to large bioreactors.  This allows researchers and GMP facilities to produce higher quality and more potent T cell, stem cell, and viral-based therapies, with greater consistency at lower cost.

AVAILABILITY. 
The Expansify™ 24-well plate and 1-well plate are currently available for purchase through our website and our North American distributor, VWR, in 1-packs and 10-packs. For research use only. The Gigacell™ device will be available later this year.

LOCATION 
XDemics’ headquarters and manufacturing facility is located fifteen minutes north of the Golden Gate Bridge, in Marin County, CA.  Our main address is 1281 Andersen Drive, Suite K, San Rafael, CA 94901.  Our biological testing laboratories are located within the Buck Institute at 8001 Redwood Blvd., Novato, CA 94945.

• General inquiries: info@xdemics.com
• Technical support: support@xdemics.com

XDemics Corporation

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