XenoSTART is an industry-leading oncology  translational research organization focused on the development and utilization of PDX models. Founded in 2007, XenoSTART was created in close collaboration with The START Center, an international cancer treatment and research organization. This partnership provides the unique ability to generate clinically-relevant XenoSTART patient-derived xenograft (XPDX) models. ​

Our diverse repository of XPDX (XenoSTART PDX) models are clinically annotated and include patient treatment history and outcome. The models are characterized through genomic profiling, histologic analysis, next generation sequencing, and in vivo drug sensitivity to relevant standards of care. 

Our models can accelerate preclinical discovery and drug development through the following turn-key services: 
     In vivo PK/PD and efficacy studies
     In-licensing of models for proprietary studies
     Orthotopic and radiotherapy studies [collaboration with our partners]
     Ex vivo and organoid studies [collaboration with our partners]
     In vivo efficacy panel screens [indication or target focused]
     Cell line development
     Custom model development


Biotechnology

Clinical Trials

Health Care

Life Sciences

Research

XenoSTART

Gunaratne

Lauren Panco

Michael Wick

Alyssa Simonson

This department focuses on the integration of bioinformatics with scientific and technical strategies to enhance research and development initiatives.

Bioinformatics and Scientific Affairs

This department manages and oversees clinical program activities and project execution.

Clinical Coordination

This department conducts in vivo studies and supports various research initiatives.

XenoSTART

Org chart

Teams

Bioinformatics and Scientific Affairs

Clinical Coordination

Research Operations

Offices

XenoSTART

Org chart

Teams

Bioinformatics and Scientific Affairs

Clinical Coordination

Research Operations

Offices

Related companies