Zag Bio is a group of bold scientists and expert drug developers, formed to pioneer thymus-targeted medicines to treat and prevent autoimmune diseases. We have discovered a novel therapeutic approach to restore central immune tolerance by creating bifunctional antibodies that deliver self-antigens to specialized antigen-presenting cells in the thymus. This enables us to harness the body’s natural process for training immune cells to recognize and tolerate self, halting or preventing autoimmune attacks on the body’s own tissues. Zag Bio’s pipeline includes its lead program ZAG-101, a bifunctional antibody that delivers pancreatic beta cell antigens to the thymus to treat Type 1 diabetes, as well as discovery programs for thymus-targeted therapies to address other autoimmune diseases.
 
Zag Bio is located in Cambridge, MA, and is supported by a broad syndicate of life sciences investors. Zag Bio’s team is built on the mission of improving the lives of patients by charting a new direction for better therapies for autoimmune diseases, based on unique insights and understanding of the biology of the thymus.

Zag Bio

Jason Cole

This department focuses on scientific research and technological development to advance the organization's innovative capabilities.

Research and Development

This department oversees the organization's board activities and ensures compliance with governance practices.

Board Governance

This department oversees the administration and management of clinical processes and procedures to ensure effective healthcare delivery.

Clinical Operations

This department provides strategic direction and oversight for the organization.

Executive Leadership

This department oversees strategic direction and management across various organizational functions.

Leadership Group

This department conducts scientific research and experimentation to advance knowledge and innovation.

Zag Bio

Org chart

Teams

Research and Development

Board Governance

Clinical Operations

Executive Leadership

Leadership Group

Research Science

Offices

Zag Bio

Org chart

Teams

Research and Development

Board Governance

Clinical Operations

Executive Leadership

Leadership Group

Research Science

Offices

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