David O'Keefe

Advent Bioservices began activity as a cell therapy contract development & manufacturing organisation (CDMO) in 2016. We are currently building a state-of-the-art facility for multiproduct GMP production outside Sawston in Cambridgeshire, which will allow scale up of current commercial production and initiate the provision of contract manufacturing services to meet the growing demand for such services in the UK. The Sawston facility is located just 7 miles outside Cambridge city centre with excellent transport links to Central London, London Stansted airport and it is 4 miles from the M11 motorway, linking to the Midlands by the new A14 extension. The facility consists of GMP lab space and process development and additional areas for future expansion. Initial construction work has focused on the building of 2 separate GMP suites with grade B/C classified areas, in house QC testing and office space as well as a multipurpose cryogenic storage unit. The entire facility will operate under a comprehensive IT infrastructure including eQMS and an eBMR, with a LIMS with secure storage for client documents and paperless systems. Clients operating within these suites will benefit from already validated cleanrooms, in-house environmental monitoring system as well as training, ancillary services and technical support inclusive of process development and validation. Our cryogenic facilities are available to external clients as off-site storage and offer disaster recovery services as per UK regulatory (HTA) requirements.