Karen Firestone

Karen Firestone began serving as a director of Amylyx in 2023. Ms. Firestone is Chairman, CEO, and co-founder of Aureus Asset Management, an investment firm that manages over $6 billion of assets for families, individuals, and non-profit entities. Previously, she spent 22 years at Fidelity Investments, most recently as a diversified fund manager of Destiny 1 Fund, the Large Cap Fund, Advisor Large Cap Fund and managing numerous sector funds, including Biotechnology, Health Care, and Media. Ms. Firestone’s Fidelity career began as an assistant fund manager to Peter Lynch on the Magellan Fund. She was twice named to the Institutional Investor “Best of the Buy Side” All Star team. In 2022, Ms. Firestone was named to the Forbes 50 Over 50 list of women, recognizing achievements occurring from age fifty and beyond.

Ms. Firestone is a regular contributor on CNBC, where she appears on Half Time Report, Squawk Box, and Worldwide Exchange, and writes for the website CNBC.com. Ms. Firestone’s book, Even the Odds: Sensible Risk Taking in Business, Investing, and Life, was published by Bibliomotion in 2016. She gave a TEDx talk on “Becoming a Sensible Risk-Taker.”

Ms. Firestone is a Director of the Boys and Girls Clubs of Boston, Director and Chair of the Audit Committee of Hamilton Thorne Ltd. (HTLZF), and serves as a Trustee Emerita at the Beth Israel Deaconess Medical Center. She is a member of the Boston Athletic Association. Ms. Firestone received a Bachelor of Arts degree in economics, magna cum laude, from Harvard College and an MBA from Harvard Business School.