Andon Bio is building an early warning system for protein expression failure, making the supply and demand of translational resources visible for the first time at the molecular level. Using a nanopore sequencing method developed at the University of Colorado Anschutz Medical Campus, Andon directly measures tRNA charging — the molecular signal that reveals whether cells have the resources they need to efficiently produce proteins. This data powers a predictive engine that replaces guesswork with real measurements, helping companies improve protein yield and cut costly development cycles.

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