Bradley E. Bernstein is an institute member at the Broad Institute and a professor in the Department of Pathology at Massachusetts General Hospital and Harvard Medical School. He co-directs the Broad’s Epigenomics Program and interacts extensively with the Cell Circuits Program, the Cancer Program, and the Klarman Cell Observatory. His research is focused on chromatin and epigenetic regulation in normal and malignant stem cells. The laboratory applies high-throughput genomic technologies to study the role of chromatin in the regulation of cell fates, functional phenotypes and drug sensitivity. The group has introduced new technologies for mapping chromatin structure genome-wide and for locus-specific editing of chromatin modifications. Dr. Bernstein’s work has received several honors including a Howard Hughes Postdoctoral Research Fellowship for Physicians, a Career Award in the Biomedical Sciences from the Burroughs Wellcome Fund, a junior faculty award from the Culpeper Foundation, election into the American Society for Clinical Investigation, and an Early Career Scientist award from the Howard Hughes Medical Institute. Dr. Bernstein received his B.S. from Yale University in physics and his M.D. and Ph.D. from the University of Washington School of Medicine.