Sandeep Kakade

Sandeep Kakade has extensive work experience in the field of biomedical engineering and pharmaceutical development. Sandeep started their career as a Process Development Engineer at Bio-gen Extracts India Ltd in 2000, where they focused on process control and optimization of the solvent extraction process for the production of drugs from herbal plants. Sandeep also gained experience in process scale-up, bioreactor design, and analytical and biological purification assays.

In 2003, Sandeep joined Interplex India Inc as a Process Engineer, where they were involved in process control and optimization, materials selection, and design and development activities for the reduction of precious metal loss in plating baths. Sandeep utilized electrochemical plating, chemical etching, and photolithography techniques for the fabrication of printed circuit boards and electronic components.

From 2004 to 2007, Sandeep worked as a Graduate Research Assistant at Wayne State University. During this time, they focused on the development of a microcapsule-based DNA immunization system using layer-by-layer self-assembly processes. This system involved the use of biodegradable and non-biodegradable polymeric microparticles for the delivery of DNA vaccines.

Following their research assistant role, Sandeep joined Purdue University as a Research Assistant in 2007. Here, they worked on the development of a highly sensitive cardiac troponin-I biosensor using superparamagnetic iron oxide microparticles and nanoporous alumina membranes. The biosensor aimed to concentrate cardiac troponin-I from blood serum for detection.

In 2008, Sandeep became a Graduate Research Assistant at Iowa State University, where they focused on the development of a single quantum dot-smFRET-based bionano-sensor for monitoring the proteolytic activity of matrix metalloproteinase. Sandeep utilized single molecule fluorescence resonance energy transfer and total internal reflection fluorescence microscopy techniques in conjunction with biocompatible quantum dots for single molecule detection and imaging.

From 2011 to 2015, Sandeep worked as a Lab Manager in the GEAR Center and Biomedical Engineering Department at the University of South Dakota. Their main focus was on the development of polymer-free platforms for the delivery of cardiovascular drugs from cobalt-chromium metal alloy substrates. Sandeep studied the drug release kinetics using high-performance liquid chromatography.

In 2015, Sandeep served as a Research Assistant at the Nanotechnology Innovation Center at Kansas State University. Their research involved studying the effects of protein corona (human plasma and human serum albumin) on the cellular uptake of superparamagnetic iron oxide nanoparticles. Sandeep also assessed the toxicity of these nanoparticles on human epidermal keratinocytes.

From 2016 to 2018, Sandeep worked as a Researcher at the University of Michigan Biomedical Engineering department. Their research focused on the development of drug-free, biodegradable PLGA nanoparticles for cellular reprogramming of innate immune cells against inflammatory diseases. This work resulted in the publication of a manuscript in the "Biomaterials" journal.

In 2018, Sandeep joined Cour Pharmaceutical Development Company, Inc. as a Senior Formulations & Product Development Scientist. Sandeep was responsible for the formulation and physicochemical characterization of multiple antigens using biodegradable polymeric microparticles synthesized through various methods. Their work involved collaborations with The Shea Lab at the University of Michigan.

Overall, Sandeep Kakade has a diverse range of experience in pharmaceutical development, nanotechnology, biosensors, and process engineering. Their expertise lies in formulation development, drug delivery systems, and the characterization of nanoparticles.

Sandeep Kakade has a strong educational background with degrees in various fields of study. Sandeep completed their Master's degree in Chemical Engineering from Iowa State University, from 2008 to 2011. Prior to that, they pursued a Master's degree in Materials Science and Engineering from Wayne State University, from 2004 to 2007. Their Bachelor's degree in Chemical Engineering was obtained from B. M. S. College of Engineering during the years 1997 to 2001. Sandeep's educational journey began at Chinmaya Mission High School, where they completed their High School education in the field of Physical Sciences between 1986 and 1995. Another mention is their studies at Wayne State University, although the exact years and degree name are not specified.