Charlie Rudin is the Chief of the Thoracic Oncology Service at Memorial Sloan Kettering Cancer Center, where he also co-directs the Druckenmiller Center for Lung Cancer Research. As a physician-scientist, he is focused on developing novel treatment options for lung cancer, including discovery of epigenetic changes that lead to therapy resistance, and development of a new strategy for in vivo genome editing of patient-derived cancer models. Charlie also chairs the NCI Small Cell Lung Cancer Research Consortium. The son of two prominent mathematicians, Charlie determined he lacked the math gene, and settled for working on curing cancer instead.