Joe Lyssikatos

Prior to co-founding Enliven, Joe served as Vice President of Medicinal Chemistry and DMPK at Biogen. Joe has also worked as a Staff Scientist at Genentech and Senior Director at Array Biopharma. He began his pharmaceutical career as a medicinal chemist at Pfizer Groton.

Joe has experience in multiple therapeutic areas, including antibiotics, immunology, cancer, and neuroscience.

Joe has led and been a key scientific contributor to over 30 programs, which have resulted in the discovery of 15 clinical candidates, most notably: Koselugo™ (selumetinib), Mektovi® (binimetinib), Tukysa® (tucatinib), crenolanib, BIIB091, varlitinib tosilate, filanesib, and motolimod.

Joe is a co-inventor/co-author on over 220 issued patents and papers.

Joe earned a PhD in Chemistry at the University of California, Berkeley, and a Bachelor of Science in Chemistry at the College of William and Mary in Williamsburg, VA.