Karen Bush

Clinical Board Member at Entasis Therapeutics

Karen Bush, Ph.D., is a Fellow of the American Academy of Microbiology and a Professor of Practice in the biotechnology program in the Department of Molecular and Cellular Biology at Indiana University, where she is also an Adjunct Professor of Biology. She currently leads a small research group that evaluates new antibacterial agents and novel resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE). Dr. Bush was involved with pharmaceutical research from 1973 to 2009, primarily working in the area of antibiotic drug discovery and development at Squibb (Bristol-Myers Squibb), Lederle (Wyeth), Astra and Johnson & Johnson Pharmaceutical Research & Development. She is especially known for her work on beta-lactamases. Dr. Bush was a member of research teams that served to discover and/or develop aztreonam, piperacillin-tazobactam, levofloxacin, doripenem and ceftobiprole. Dr. Bush received a Ph.D. in biochemistry from Indiana University.


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