Shamim Naghdi

Shamim Naghdi, PhD joins ExpressCells from the MitoCare Center in the Department of Pathology, Anatomy and Cell Biology at Thomas Jefferson University. Dr. Naghdi has in-depth experience across the spectrum of molecular biology techniques, including primary and immortalized cell culture; plasmid transfection and RNA interference; gene-editing with CRISPR/Cas9; DNA-RNA isolation, characterization, and cloning; clone validation; and cell death and enzyme assays. To this, she adds extensive work with confocal and high content/throughput wide-field microscopy, organelle purification from primary tissues and cell lines, and in vivo studies. Her work at the MitoCare Center focused on characterizing mitochondrial cell death pathways in hepatocarcinoma (HCC), and drug-candidate screening in a high-throughput imaging model quantifying cell death in HCC. Dr. Naghdi received her PhD from the University of Graz, Austria. Her most recent publications have appeared in journals such as Cell Death & Disease, EMBO Molecular Medicine, and PNAS.