David R. Brennan

Mr. Brennan joined our board in May 2014, bringing more than 37 years of experience in the pharmaceutical industry. He was appointed lead independent director in November 2018. From 2006 to 2012, Mr. Brennan was the Chief Executive Officer of AstraZeneca PLC, a global biopharmaceutical company. Previously at AstraZeneca, Mr. Brennan served as Executive Vice President of North America from 2001 to 2006; and as Senior Vice President of Commercialization and Portfolio Management from 1999 to 2001. Mr. Brennan also served as a member of the board of directors of AstraZeneca from 2005 to 2012. Prior to AstraZeneca, Mr. Brennan held various positions at Astra Pharmaceuticals, L.P., Astra Merck, Inc. and Merck and Co. Inc. Mr. Brennan also currently serves as chairman of the board of directors of Alexion Pharmaceuticals (Nasdaq: ALXN) and previously served as Interim CEO from December 2016 to March 2017. Mr. Brennan received a B.A. in Business Administration from Gettysburg College. He is a member of the Compensation Committee.