Guy is recognized worldwide as one of the best specialists in column generation. His main research interests are in the areas of large-scale optimization, integer programming, combinatorial optimization, and constrained shortest path problems with applications to vehicle routing and crew scheduling in the ground, air, rail, and maritime transportation, as well as to personnel scheduling. He has been involved in several industrial projects with companies developing software for airlines (AD OPT), public transit and postal agencies (Giro), and personnel scheduling (Kronos), directly with Rio Tinto and Via Rail, among others. From 2015 to 2019, he was the Director of the GERAD research center which gathers 70 professors and 450 graduate students performing research on the mathematics of decision-making. He co-authored more than 125 scientific papers. Since 2000, Guy is a professor in the Department of Mathematics and Industrial Engineering (MAGI) at Polytechnique Montréal.
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