Sharath Madasu is responsible for protein-based /small molecule characterization and assay development activities at Kemp Proteins. He leads the antibody characterization department in the optimization of immunoassays & biophysical assays to characterize antibody and proteins for stable cell line, humanization, reagent development, biomanufacturing process development, and host of important thereapeutic and diagnostic programs. Prior to Kemp Proteins, Sharath led a team of scientists at Ibex Biosciences in the identification of and development of new therapeutic modalities and therapeutic antibodies. As a Biomedical Scientist and life long learner, he has strong analytical skills and expertise in antibody development, biochemistry, molecular biology, confocal microscopy, western blots, QPCR, flow cytometry, cell culture, and project management. He earned his PhD in Cellular and Molecular Biologly at the University of Vermont, where he pioneered the identification of quantitative changes in protein – protein interactions and post translational modifications of Kv1.2 proteome in ex-vivo pharmacological stimulation using bottom up quantitative Mass spectrometry and identified potential biomarkers for drug targeting.
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