Sung Hugh Choi

Sung Hugh Choi has a broad work experience in the field of medical research and drug discovery. Sung Hugh started as a research assistant at Ewha Womans University in 2000, where they identified novel genes involved in osteoclast differentiation and developed a therapeutic approach to suppress complex EAE. From 2002 to 2003, they worked as a research associate at Macrogen Inc. In 2003, they joined UMass Medical School as a Ph.D. student, exploring the role of phospho-regulation in chromosome segregation, and later as a postdoctoral associate, investigating spindle elongation forces in chromosome instability and proposing that small molecule inhibitors for microtubule motors may enhance current tumor therapeutics. From 2011 to 2016, they served as a Research Fellow at Massachusetts General Hospital, developing stem cell-mediated drug delivery systems in mouse brain tumor models. In 2017, they became an Instructor at Brigham and Women's Hospital, where they developed immune oncology therapies for enhancing T cell activation and infiltration into the tumor microenvironment, developing chimeric antigen receptor T cell therapy in a mouse model of glioblastoma and identified peritumoral immune reactions post-cytoreductive surgery to boost anti-cancer immune response. From 2018 to 2019, they were the Principal Scientist at Genosco, where they led drug discovery of small molecule IO pipelines, managed multiple CROs, and finalized amendment reports for IND filings of Janssen's Lazertinib. Currently, they are the Director of Biology and Strategic Alliances at PineTree Therapeutics Inc, where they lead MOA research and protein engineering teams for bispecific antibody pipeline, co-leads a Bits and Bytes Grant program with the University of Massachusetts Boston research team, and develops immune checkpoint inhibitor bispecific antibody for cancer immunotherapy.

Sung Hugh Choi received their Master of Science degree in Biochemistry from Korea University in 2000. Sung Hugh then went on to study at UMass Chan Medical School, where they earned their Doctor of Philosophy degree in Cell Biology in 2010.