Dr. Machajewski brings over 20 years of experience in medicinal chemistry and small molecule drug discovery across multiple therapeutic areas including metabolic, anti-infective and oncology. Dr. Machajewski joined Pliant in 2018 and during his tenure of roles of increasing responsibility he effectively led cross-functional project teams from target validation to Phase 1 including work on Pliant’s NASH and αVβ8/1 oncology programs. In his current role, Dr. Machajewski leads the medicinal, analytical, chemical informatics and computational chemistry teams in support of Pliant’s strategic initiatives. Prior to joining Pliant, Dr. Machajewski held leadership roles of increasing responsibility at Novartis and Chiron and Achaogen where he led and managed teams advancing the companies’ early-stage portfolios into the clinic. Dr. Machajewski received his BS in chemistry (highest honors) from the University of Texas at Austin, his Ph.D. in organic chemistry from Stanford University and completed postdoctoral studies at The Scripps Research Institute.
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