Prime Medicine
Leslie Houghton, Ph.D., currently serves as the mRNA Production and Process Development professional at Prime Medicine, Inc. since November 2021. Prior to this role, Houghton was an Investigator II at Novartis Institutes for BioMedical Research (NIBR) from 2013 to 2018, where work focused on mRNA synthesis, establishing a synthesis core, and leading a team to enhance process efficiency and reduce costs. Houghton also held the position of Technical Instructor at the Massachusetts Institute of Technology from 2009 to 2013, overseeing and mentoring undergraduate research projects. Houghton holds a Doctor of Philosophy in Biology from Boston University and completed a postdoctoral fellowship in Dermatology at the Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School.
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Prime Medicine
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Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA. A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations. We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients. Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.