X4 Pharmaceuticals
Margo Jaffee currently serves as Vice President of Clinical Operations at X4 Pharmaceuticals since February 2024. Previously, Margo held vice president roles at Moderna, focusing on Clinical Trial Excellence and Support as well as leading Clinical Operations for Rare Disease, Autoimmune, and Emerging Therapeutics. Margo's career also includes key positions at Takeda, Shire, Novartis, Accentia Biopharmaceuticals, PAREXEL, and Dana-Farber Cancer Institute, with responsibilities ranging from clinical program management to clinical research coordination. Margo holds educational credentials from Boston University and an online certificate in Immunology from Harvard Medical School.
X4 Pharmaceuticals
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X4 Pharmaceuticals is developing novel therapeutics designed to improve immune cell trafficking to treat rare diseases, including primary immunodeficiencies and certain cancers. The company’s oral small molecule drug candidates antagonize the CXCR4 pathway, which plays a central role in immune surveillance.