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Brian Vash

Associate at Apple Tree Partners

Brian Vash is an entrepreneur in residence at ATP focusing on innovative protein engineering. Brian has more than 20 years of hands-on experience designing and producing novel proteins, including 18 years in the pharmaceutical industry contributing to drug discovery pipelines and intellectual property. Before joining ATP, Brian was an early member of the leadership team at Elstar Therapeutics, where as director of protein engineering and technology development, he was responsible for establishing the company’s protein engineering and biologics production functions. Brian played a critical role in the development of Elstar’s novel kappa/lambda bispecific antibody platform, along with other innovative protein designs. Prior to that he spent 12 years at Novartis as a scientist working on structural biology and biologics, contributing to both the small molecule and protein therapeutics pipelines. While at Novartis, Brian was an inventor on patents covering alternative scaffolds, therapeutic proteins, and CAR-T therapy.

Brian earned a BS in biochemistry from the University of Texas at Arlington


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