Karen E. Knudsen

Dr. Knudsen is the Director of the Sidney Kimmel Cancer Center and the Hilary Koprowski Chair of the Department of Cancer Biology at Thomas Jefferson University. Dr. Knudsen’s research focuses on androgen receptor (AR) signaling in prostate cancer, to delineate the molecular mechanisms driving androgen dependence. Her research identifying tumor suppressor and hormone receptor alterations has revealed novel targets for treating this disease, leading to biomarker-driven clinical trials. Dr. Knudsen also has joint appointments in the Departments of Urology, Radiation Oncology, and Medical Oncology. Additionally, she served as the first Vice Provost for Thomas Jefferson University, overseeing and integrating basic and clinical research across the colleges.