Mike Perkins

In September 2019, Mike joined ATXA as an advisory chief medical officer (CMO). Mike has extensive experience in CV & respiratory medicine, academia, large pharma (e.g Pfizer), start-ups (Oxygen Ltd, UK) and has held various CMO consultancies since 2004. Dr Perkins is an experienced pharmaceutical physician in CV & respiratory medicine having worked in the large pharmaceutical for more than 30 years. He previously held senior positions in Clinical and Regulatory at AstraZeneca and Pfizer. Whilst at Pfizer, as Vice President Regulatory Affairs, he was a member of the world-wide exploratory development forum (EDF) overseeing many projects including the Sildenafil programme in pulmonary hypertension which was delivered from the Pfizer Sandwich Laboratories Development research hub. He also has extensive experience in academic medicine, including acting as an experienced appraiser for General Medical Council physician revalidation for the Faculty of Pharmaceutical Medicine and a Medical Appraisal Lead.

In 2004, Dr Perkins transitioned successfully from large Pharma into biotech and has managed preclinical and clinical programmes to proof of mechanism and proof of concept in pain, allergy and inflammation. He has been CMO for several biotech companies. He was previously CMO for Oxagen Ltd (an Oxford University spin out) where he devised and managed a clinical programme from preclinical to first-in-human, Phase II POC and Phase IIb for a novel CRTH2 antagonist. Prior to this, he was Chief Development Officer for Ionix Pharmaceuticals in Cambridge where he devised and ran a clinical programme for intranasal buprenorphine in the USA including filing an IND and managing a pre-submission IND meeting involving three FDA divisions. As advisory CMO at ATXA, Mike’s main responsibilities includes advice on finalizing the design of the FIH Phase 1 clinical trial and selection of the clinical trial unit, as well as liaising with key clinical advisors and with the national competent authority where the FIH trial will be carried out (e.g. the MHRA, UK or HPRA, Ireland).