Michael R. Knowles

Dr. Michael R. Knowles is a Professor of Pulmonary and Critical Care Medicine at the University of North Carolina. He has over three decades of clinical research experience that spans the disciplines of biology, physiology, and design of clinical trials in both the academic and private sectors. He is currently the head of two large multicenter studies: 1) Genetic Modifiers of Disease phenotype (severity) in cystic fibrosis lung and liver disease, which also includes a recently formed International Consortium doing a whole-genome scan; and 2) a Consortium with 8 sites in North America to study rare genetic disorders of mucociliary clearance. He received his B.A. and M.D. from the University of North Carolina at Chapel Hill, Chapel Hill, NC, completed his Residency in Internal Medicine at Duke University, Durham, NC, and finished his Fellowship in pulmonary diseases at the University of North Carolina at Chapel Hill. Dr. Knowles has authored over 100 papers over the course of his career.