At DICE Therapeutics, we design and develop innovative therapies in immunology for patients with debilitating disease. Seeking to create a future where convenient oral medicines with biologic-like efficacy are available to patients with serious medical conditions, we are developing oral alternatives to medicines currently limited to injectable forms. We believe that such pills will be widely appreciated by patients and doctors alike, as they provide a lower bar to entry than biologics, and as oral medicines can easily be co-formulated with other efficacious drugs.
The combination of our core technology with additional, unique biophysical insights has enabled DICE to target protein-protein interactions with small molecules. In doing so, DICE has cracked open a previously intractable set of clinically validated therapeutic targets, including Interleukin-17 (IL-17). Our lead program – an orally bioavailable IL-17 antagonist for the treatment of psoriasis – is currently progressing through IND-enabling studies. In parallel, we continue to advance both partnered and internal pipeline drug discovery programs, providing a robust pre-clinical pipeline.

Biotechnology

DICE Therapeutics

J. Kevin Judice

Christian Puccetti

Christy Shoung

Ram Devarapalli

Paula Opal

Jeffrey Enejosa, MD

Mary Riley

Nico Ghilardi

Venkat Thalladi

John Jacobsen

Tim Lu

Scott Robertson

The Research and Development team at DICE Therapeutics is focused on designing and optimizing innovative oral therapies for immunological conditions. Comprising specialists in medicinal chemistry, protein chemistry, and pharmacology, the team collaborates to discover and develop small molecules that effectively target protein-protein interactions, including the critical Interleukin-17 pathway. Their work drives the pre-clinical advancement of novel drug candidates, paving the way for next-generation therapies that offer patients convenient and effective treatment options.

Research and Development

Clinical Operations and Support

Board and Executive Management

Research and Development

About

Team members

Other teams at DICE Therapeutics

Clinical Operations and Support

Board and Executive Management