Alexander Alex

Alexander is an accomplished and innovative scientific leader who has successfully applied a very broad range of computational chemistry approaches to drug discovery projects. He joined Pfizer R&D and went onto gain extensive experience in computational chemistry approaches applied to the discovery of novel, small-molecule drug candidates against a wide range of biological targets leading to, for example, enzyme inhibitors, GPCR antagonists as well as ion-channel modulators. He developed and implemented innovative ideas in areas including virtual screening and ADME modeling, resulting in over 30 publications. He implemented the concept of "ligand efficiency" as a general compound design principle, which is now widely used in the Medicinal Chemistry community. Alexander has considerable scientific leadership experience and has previously held the senior positions of Director and Research Fellow, Head of Computational Chemistry lup to 15 computational chemists), Matrix Leader of Computational Chemistry at Sandwich as well as Leader of the Global Computational Chemistry Discipline lover 100 scientists).