Emergex Vaccines
Lorraine Mumtaz is a seasoned professional in clinical program management and research, currently serving as a Clinical Programmes Manager at Emergex Vaccines since November 2020. Prior experience includes roles as a Clinical Research Associate at the same organization and as a Clinical Trials Associate at PsiOxus Therapeutics Ltd. Lorraine has also held positions such as Clinical Trials Manager at the Oxford Respiratory Trials Unit and Clinical Trials Administrator at OCDEM. Earlier in their career, Lorraine worked as a Research Centre Administrator and Trials Administrator at the University of Oxford. Lorraine holds a Bachelor's degree in Psychology & Visual Studies from Oxford Brookes University, obtained between 1992 and 1995.
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Emergex Vaccines
Emergex, a clinical-stage, privately-held biotechnology company headquartered in Abingdon, UK, with an operating subsidiary in Doylestown, Pennsylvania, USA, is pioneering the development of 100% synthetic T cell-priming immune set-point vaccine candidates that harness and direct the body’s natural CD8+ T cell immune response to destroy and clear pathogen-infected cells in order to provide protection against some of the world’s most urgent health threats. First indications pursued are against infectious diseases caused by: [i] viruses, amongst which are Betacoronavirus, Dengue Fever and Universal Influenza A, including pandemic influenza, as well as [ii] intra-cellular bacteria. Emergex has a growing proprietary pipeline of innovative T cell-priming set-point candidates that have the potential to deliver rapid, broad (strain and variant agnostic) and long-lasting prevention and therapy to reduce serious illness associated with infectious disease. Emergex has completed two Phase I clinical trials for products against: [i] Dengue (which may also be disease-modifying for other members of the Flaviviridae virus family) and [ii] Betacoronavirus disease. Other programmes in development include candidates for Universal (including pandemic) Influenza, Zika, Chikungunya, Smallpox/Monkeypox, Hand/Foot/Mouth Disease a booster for Yellow Fever, and Francisella tularensis (intra-cellular bacterium). Emergex’s T cell-priming immune set-point candidates combine two proprietary technologies, [i] an empirically determined library of pathogen-derived protein fragments expressed on the surface of pathogen-infected cells (forming the MHC Class I expression “ligandome” library) using Immunotope Inc’s immunoproteomics technologies, and [ii] a self-assembling, ultrasmall carbohydrate-passivated nanocluster carrier system designed to deliver synthetic peptides to the skin-resident immune system via micro-needles to elicit a robust T cell response.